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Toward a national eDNA strategy for the United States

Environmental DNA (eDNA) data make it possible to measure and monitor biodiversity at unprecedented resolution and scale. As use-cases multiply and scientific consensus grows regarding the value of eDNA analysis, public agencies have an opportunity to decide how and where eDNA data fit into their mandates. Within the United States, many federal and state agencies are individually using eDNA data in various applications and developing relevant scientific expertise. A national strategy for eDNA implementation would capitalize on recent scientific developments, providing a common set of next-generation tools for natural resource management and public health protection. Such a strategy would avoid patchwork and possibly inconsistent guidelines in different agencies, smoothing the way for efficient uptake of eDNA data in management. Because eDNA analysis is already in widespread use in both ocean and freshwater settings, we focus here on applications in these environments. However, we foresee the broad adoption of eDNA analysis to meet many resource management issues across the nation because the same tools have immediate terrestrial and aerial applications.

Environmental DNA

P- and S-wave velocity estimation by ensemble Kalman inversion of dispersion data for strong motion stations in California

This study uses an ensemble Kalman method for near-surface seismic site characterization of 154 network earthquake monitoring stations in California to improve the resolution of S -wave velocity ( V S ) and P -wave velocity ( V P ) profiles—up to the resolution depth—coupled with better quantification of uncertainties compared to previous site characterization studies at this network. These stations were part of the Yong et al . site characterization project, with selected stations based on future recordings of ground motions that are expected to exceed 10 per cent peak ground acceleration in 50 yr. To estimate V S and V P from experimental dispersion data, Yong et al . investigated these stations using linearized (local search and iteration) routines, and Yong et al . later studied a subset of these stations using nonlinear (global search and optimization) routines. In both studies, the selection of model parameters—that is, discretization of the V S and V P profiles with only five fixed thickness layers—was mainly based on trial and error. In contrast, this paper uses an approximate Bayesian method to assimilate experimental dispersion data and sequentially update an ensemble of particle estimates that span the V S and V P parameter spaces. Doing so, we systematically determine the most probable profiles conditioned on the experimental dispersion data, the introduced noise levels, and a priori knowledge in the form of physical constraints. We consider two configurations to discretize the soil depth from the surface to half of the maximum discernible wavelength obtained from the experimental dispersion data, namely refined and coarse models, and two initial models for each configuration to study solution multiplicity. Our results suggest that using the refined model for the top surface layers improves the resolution of near-surface site characteristics and the model’s success rate in capturing dispersion data at high frequencies. All models result in similar V S but distinct V P profiles, with increasing uncertainty at deeper layers, suggesting that the fundamental mode of Rayleigh wave dispersion data is not adequate to constrain the P -wave velocity profile and the S -wave velocity close to the resolution depth.

California

Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination

In Spring 2021, the highly transmissible SARS-CoV-2 Delta variant began to cause increases in cases, hospitalizations, and deaths in parts of the United States. At the time, with slowed vaccination uptake, this novel variant was expected to increase the risk of pandemic resurgence in the US in summer and fall 2021. As part of the COVID-19 Scenario Modeling Hub, an ensemble of nine mechanistic models produced 6-month scenario projections for July–December 2021 for the United States. These projections estimated substantial resurgences of COVID-19 across the US resulting from the more transmissible Delta variant, projected to occur across most of the US, coinciding with school and business reopening. The scenarios revealed that reaching higher vaccine coverage in July–December 2021 reduced the size and duration of the projected resurgence substantially, with the expected impacts was largely concentrated in a subset of states with lower vaccination coverage. Despite accurate projection of COVID-19 surges occurring and timing, the magnitude was substantially underestimated 2021 by the models compared with the of the reported cases, hospitalizations, and deaths occurring during July–December, highlighting the continued challenges to predict the evolving COVID-19 pandemic. Vaccination uptake remains critical to limiting transmission and disease, particularly in states with lower vaccination coverage. Higher vaccination goals at the onset of the surge of the new variant were estimated to avert over 1.5 million cases and 21,000 deaths, although may have had even greater impacts, considering the underestimated resurgence magnitude from the model.

eLife