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K.S. Pilcher

Publications and source records attributed to K.S. Pilcher.

4 recordsLinked to original sources

An antigenic comparison between infectious hematopoietic necrosis virus (OSV strain) and the virus of haemorrhagic septicaemia of rainbow trout (Salmo gairdneri) (Denmark strain) by cross neutralization

The infectious hematopoietic necrosis virus (OSV strain) and the virus of haemorrhagic septicaemia of rainbow trout ( Salmo gairdneri ) (Denmark strain) were examined for possible antigenic relationship by plaque neutralization using homologous and heterologous antisera. No neutralization of either virus was observed on exposure to heterologous antiserum. This indicates that there is no antigenic relationship between these two viruses as determined by this method.

Journal of Wildlife Diseases↗

Studies of certain sulfonamide drugs for use in juvenile chinook salmon

Sulfamethazine, introduced to fishery medicine by Snieszko and Friddle in 1950, has been widely accepted for treatment of systemic bacterial infections of fish. When administered to fish in their diet, this drug is effective against susceptible bacteria but has the disadvantages of being slowly absorbed (Snieszko and Friddle, 1951) and relatively toxic (Wood, Yasutake, and Johnson, 1957). Today there are many sulfonamides which are more efficacious than sulfamethazine. In domestic animals, sulfisoxazole and sulfadimethoine are absorbed quickly from the gastrointestinal tract and have fewer toxic side reactions, a wider antibacterial spectrum, and better bacteriostatic activity. In the work described in this paper, the efficacies of sulfisoxazole and sulfadimethoxine were compared to the efficacy of sulfamethazine. Experiments were designed to determine the rate of intestinal absorption, the rate of elimination from the blood, the effect on growth, and the toxicity of each drug in juvenile chinook salmon ( Oncorhynchus tshawytscha ). The comparative bacteriostatic activity against two common fish pathogens was also determined for each drug.

Progressive Fish-Culturist↗

A comparison of Oregon pellet and fish-meat diets for administration of sulfamethazine to Chinook salmon

The absorption of sulfamethazine by yearling spring chinook salmon ( Oncorhynchus tshawytscha ) was compared when administered in the Oregon Pellet and a fish-meat diet. The pelleted diet delivered the drug to the fish approximately twice as efficiently as the fish-meat diet. Dosage levels are recommended for both diets, and the efficacy of administering drugs in fish feed is discussed.

Oregon↗