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John Hughes-Clarke

Publications and source records attributed to John Hughes-Clarke.

5 recordsLinked to original sources

Evaluating baits with lufenuron and nitenpyram for flea control on prairie dogs (Cynomys spp.) to mitigate plague

Plague, caused by Yersinia pestis , is a widespread threat to endangered black-footed ferrets ( Mustela nigripes ) and their primary prey, prairie dogs ( Cynomys spp.). Wildlife biologists most commonly manage plague using insecticides to control fleas, the primary vectors of Y. pestis . We tested edible baits containing the insecticides lufenuron and/or nitenpyram in prairie dogs. During a laboratory study, we treated 26 white-tailed prairie dogs ( Cynomys leucurus ) with lufenuron at 300 mg/kg body mass. All animals remained clinically healthy over the 9 wk monitoring period. Although serum lufenuron concentrations were >130 ppb in two treatment groups at week 1, concentrations declined to ≤60 ppb after 3 wk in non-torpid prairie dogs and after 7 wk in torpid prairie dogs. In a field experiment, we tested baits containing a combination of 75 mg lufenuron and 6 mg nitenpyram, respectively, in black-tailed prairie dogs ( Cynomys ludovicianus ). We uniformly distributed baits at 125 baits/ha on two plots (treated once) and 250 baits/ha on two plots (each treated twice 4.4 wk apart). Following treatments, flea abundance increased on prairie dogs and remained stable in burrows. Our findings indicate that baits containing lufenuron and nitenpyram, at the reported treatment rates, are ineffective tools for flea control on prairie dogs. Future experiments might evaluate efficacy of higher doses of lufenuron and nitenpyram, and repetitive treatments at differing intervals over time to evaluate potentially therapeutic treatments.

Journal of Wildlife Diseases

Exploring and mitigating plague for One Health purposes

Purpose of Review In 2020, the Appropriations Committee for the U.S. House of Representatives directed the CDC to develop a national One Health framework to combat zoonotic diseases, including sylvatic plague, which is caused by the flea-borne bacterium Yersinia pestis . This review builds upon that multisectoral objective. We aim to increase awareness of Y. pestis and to highlight examples of plague mitigation for One Health purposes (i.e., to achieve optimal health outcomes for people, animals, plants, and their shared environment). We draw primarily upon examples from the USA, but also discuss research from Madagascar and Uganda where relevant, as Y. pestis has emerged as a zoonotic threat in those foci. Recent Findings Historically, the bulk of plague research has been directed at the disease in humans. This is not surprising, given that Y. pestis is a scourge of human history. Nevertheless, the ecology of Y. pestis is inextricably linked to other mammals and fleas under natural conditions. Accumulating evidence demonstrates Y. pestis is an unrelenting threat to multiple ecosystems, where the bacterium is capable of significantly reducing native species abundance and diversity while altering competitive and trophic relationships, food web connections, and nutrient cycles. In doing so, Y. pestis transforms ecosystems, causing “shifting baselines syndrome” in humans, where there is a gradual shift in the accepted norms for the condition of the natural environment. Eradication of Y. pestis in nature is difficult to impossible, but effective mitigation is achievable; we discuss flea vector control and One Health implications in this context. Summary There is an acute need to rapidly expand research on Y. pestis , across multiple host and flea species and varied ecosystems of the Western US and abroad, for human and environmental health purposes. The fate of many wildlife species hangs in the balance, and the implications for humans are profound in some regions. Collaborative multisectoral research is needed to define the scope of the problem in each epidemiological context and to identify, refine, and implement appropriate and effective mitigation practices.

Current Tropical Medicine Reports

Timing and patterns of basin infilling as documented in Lake Powell during a drought

Between 1999 and 2005, drought in the western United States led to a >44 m fall in the level of Lake Powell (Arizona-Utah), the nation's second-largest reservoir. River discharges to the reservoir were halved, yet the rivers still incised the tops of deltas left exposed along the rim of the reservoir by the lake-level fall. Erosion of the deltas enriched the rivers in sediment such that upon entering the reservoir they discharged plunging subaqueous gravity flows, one of which was imaged acoustically. Repeat bathymetric surveys of the reservoir show that the gravity flows overtopped rockfalls and formed small subaqueous fans, locally raising sediment accumulation rates 10–100-fold. The timing of deep-basin deposition differed regionally across the reservoir with respect to lake-level change. Total mass of sediment transferred from the lake perimeter to its bottom equates to ~22 yr of river input.

Arizona, Utah

Cruise report RV Inland Surveyer Cruise IS-98; the bathymetry of Lake Tahoe, California-Nevada, August 2 through August 17, 1998, Lake Tahoe, California and Nevada

The major objective of cruise IS-98 was to map the bathymetry of Lake Tahoe, California-Nevada (Fig. 1) to fulfill a commitment made during the Lake Tahoe Presidential Forum in 1997. The only existing bathymetry of Lake Tahoe, collected in 1923, was recently compiled by Rowe and Stone (1997), but the data density is inadequate for the level of scientific studies ongoing and anticipated in the near future for Lake Tahoe. Recent advances in marine multibeam-sonar capabilities now permit a cost-effective way, to precisely map the bathymetry of large areas of the ocean floor with 100% coverage. Cruise IS-98 applied this state-of-the-art ocean technology to Lake Tahoe. The newest of these high-resolution multibeam mapping systems also simultaneously collects backscatter (similar to sidescan sonar) imagery that results in a complimentary and co-registered data set that is related to the distribution of lake-floor materials and textures. The two types of maps that resulted from this cruise provide the multidisiplinary Lake Tahoe research community an unprecedented set of base maps upon which to build their studies. This report describes the high-resolution multibeam mapping system used at Lake Tahoe, outlines the data-processing steps used to produce the maps, and includes the daily log of the cruise.

California;Nevada

Magnetic and bathymetric data from R/V FARNELLA cruises FRNL87-1, 87-2, 87-3, 87-4 and 87-5 in the U.S. Atlantic Margin EEZ, southern Blake Escarpment, and Nova Scotia continental rise

During the winter and spring of 1987, the U.S. Geological Survey, in cooperation with the Institute of Oceanographic Sciences of the United Kingdom, collected approximately 31,350 line kilometers (km) of magnetic data and approximately 32,280 line km of bathymetric data in the U.S. Atlantic Margin Exclusive Economic Zone (EEZ), Southern Blake Escarpment, and Nova Scotia Rise (Fig. 1). Collected simultaneously with the magnetic and bathymetric data was a suite of geophysical data. These geophysical datasets will be released at a later date and include GLORIA (Geological LOng-Range Inclined Asdic) sidescan-sonar digital image data, 3.5 kilohertz (kHz) high-resolution sub-bottom profiler records, 10 kHz bottom profiler records from which bathymetric data were derived, and two channel seismic-reflection profiles. Survey line spacing was about 25 km in water depths exceeding 3,000 meters (m) and gradually decreased to less than 5 km in 200 m water depths. No areas were surveyed with depths shallower than 200 m. Orientation of the tracklines varies with respect to the trend of the bathymetric contours for each of the five legs (Fig.l).

Open-File Report